Top 7 Best Alpha Lipoic Acid Reviews Of 2022

The best Alpha Lipoic acid is one that has proven to be weight loss friendly, not causing side effects like many over the counter or prescription medications. Diet, exercise, and a healthy lifestyle will help you lose weight, but constant sugar consumption can be a factor in the inability to shed pounds. Alpha lipoic acid helps to eliminate sugar cravings and is considered a safe supplement. And since Alpha Lipoic Acid actually reduces inflammation throughout the body, it assists in weight loss and as a treatment for Diabetes Type II as well as elevated LDL cholesterol and triglycerides. As it does this, it also boosts collagen levels which works to firm up skin, helping you look younger.

Best Alpha Lipoic Acid Reviews

1. Sundown Super Alpha Lipoic Acid

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Sundown Super Alpha Lipoic Acid 600 mg, 60 Capsules (Packaging May Vary) Non-GMOˆ, Free of Gluten, Dairy, Artificial Flavors
  • Supports sugar metabolism.
  • Often called the "universal antioxidant".
  • Supports nervous system health.
  • During the summer months products may arrive warm but Amazon stores and ships products in accordance with manufacturers' recommendations, when provided.
BrandSundown
Product BenefitsMetabolism Management
Item FormCapsule
Dosage FormCapsule
FlavorSundown
Allergen InformationSulphur Dioxide
Material FeatureGluten Free, Yeast Free, Lactose Free, Sugar Free
Item Weight0.1 Pounds
Unit Count60 Count
Item Dimensions LxWxH2.07 x 2.07 x 3.77 inches

Dietary Supplement. Supports antioxidant health and energy metabolism. No artificial color, flavor or sweetener, no preservatives, no sugar, no milk, no lactose, no soy, no gluten, no wheat, no yeast, no fish.-Disclaimers: ‡Clean defined as all products non-GMOˆ, and free of gluten, wheat, dairy, lactose and artificial flavors. ˆApplies to all products manufactured after 3/1/17. *These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Clean Nutrition

Sundown has been making high quality vitamins and supplements for over 40 years. We continue to work hard to provide our customers with products to complement their healthy diet and active lifestyle.

No Gluten / Wheat

All of our products are 100% Free of Gluten and Wheat

No Dairy / Lactose

All of our products are 100% Free of Dairy and Lactose

No Artificial Flavors

All of our products are 100% Free of Artificial Flavors

100% Non-GMO

All of our products are 100% Non-GMO

2. Doctor’s Best Alpha-Lipoic Acid

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Doctor's Best Alpha-Lipoic Acid, Non-GMO, Gluten Free, Vegan, Soy Free, Helps Maintain Blood Sugar Levels, 600 mg 180 Veggie Caps
  • DOCTOR’S BEST ALPHA-LIPOIC ACID (ALA) - plays an important role in the metabolism of glucose that produces cellular energy in the body. ALA is naturally occurring and functions as an antioxidant throughout the body that helps regenerate other antioxidants such as vitamin C, vitamin E and glutathione. ALA helps support the body’s potential in buffering free radicals for overall well-being.
  • SUPPORT YOUR BODY WITH ANTIOXIDANTS – ALA is a powerful antioxidant and supports the regeneration of antioxidants. Alpha lipoid acid also appears to function as a coenzyme in both antioxidant and metabolic functions. Potent antioxidant that is both a water-soluble and fat-soluble antioxidant.
  • SUPPORTS THE BODY’S DEFENSE AGAINST FREE RADICALS - recycles antioxidants such as Vitamin C and Vitamin E that have the ability to quench a wide variety of free radicals. Also supports the functioning of other antioxidants that are present in tissues and cells.
  • FREE RADICALS FOR OVERALL WELL-BEING – free-radical fighting antioxidant ALA produces energy through ALA supplementation. Helps maintain healthy glucose metabolism, supports healthy aging, cognitive function & brain health, eye health and cardiovascular health
  • During the summer months products may arrive warm but Amazon stores and ships products in accordance with manufacturers' recommendations, when provided.
BrandDoctor’s Best
Product BenefitsHeart Health Support, Metabolism Management, Brain Health Support
Item FormVeggie Cap
Dosage FormCapsule
Age Range (Description)Adult
Allergen InformationGluten Free, Soy Free
Material FeatureGMO Free, Gluten Free, Vegan
Item Weight0.37 Pounds
Unit Count180 Count
Item Dimensions LxWxH3.13 x 3.13 x 5.69 inches

Alpha-lipoic acid (ALA) is a naturally occurring antioxidant, essential for the functioning of 5 enzymes involved in glucose and amino acid metabolism.

ALA is both a coenzyme and a potent antioxidant. Mitochondria, our cells’ energy generators, use ALA for both protection and to generate cellular energy. Being active in both the water and the fatty compartments of cells, ALA fights free radicals throughout the body.

What are the benefits of Alpha-Lipoic-Acid?

  • Helps promote the body’s antioxidant defenses.*
  • Helps maintain healthy blood sugar levels already within the normal range.

Why take Alpha-Lipoic-Acid?

  • Helps the body’s defense against free radicals*
  • Recovers antioxidant nutrients such as Vitamin C and Vitamin E*
  • Aging is accompanied by a decreased ability of the liver to recycle ascorbic acid following oxidative stress.

How does it work?

  • Lipoic acid is used in the body to break down carbohydrates and to make energy for the other organs in the body*
  • Lipoic acid is a key factor in the cellular process that metabolizes glucose for energy production.*
  • Supports healthy aging – as we age, our ability to produce lipoic acid decreases.

3. Nature’s Bounty Alpha Lipoic Acid

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Nature's Bounty Alpha Lipoic Acid 200 mg 30 Capsules
  • Beneficial antioxidant support.
  • Helps your body fight free radicals.(1) Free radicals can cause oxidative stress which may damage cells.(1)
  • Non-gmo
  • These statements have not been evaluated by the Food and Drug Administration
Special IngredientsGluten Free
BrandNature’s Bounty
Specific Uses For ProductPersonal
Product BenefitsBeneficial antioxidant support.
Item FormCapsule
Diet TypePlant Based
Dosage FormCapsule
FlavorUnflavored
Allergen InformationSulphur Dioxide
Material FeatureGMO Free

Nature’s Bounty Alpha Lipoic Acid (ALA) is known as the “universal antioxidant” for its ability to work so well with other vitamin and enzyme antioxidants in your body.(1) As an revitalizing antioxidant, ALA helps fight free radicals in the body.(1) Free radicals can cause oxidative stress which may damage cells.(1) (1)These statements have not been evaluated by the Food and Drug Administration.

Driving Innovation through Scientific Expertise

Our Scientific Advisory Council is made up of prominent scientists and researchers external to The Nature’s Bounty Co., who play a key role in the Company’s product innovation and scientific advancement. It is comprised of some of the most respected medical and nutrition experts in the field.

Don’t Just Take Our Word For It

We’re proud that our facilities have been successfully audited by the United States Pharmacopeia and STR (Specialized Technology Resources), a leading independent dietary supplement quality evaluation firm.

Quality You Can Count On

Every Nature’s Bounty product is subjected to numerous quality tests and assays throughout the manufacturing process to verify purity and full potency.

4. Natrol Alpha Lipoic Acid Tr 600mg Tablets

Natrol Alpha Lipoic Acid Tr 600mg Tablets, 45-Count
  • Antioxidant Protection: The antioxidant powers infused in Natrol Alpha Lipoic Acid helps cells in the human body rejuvenate
  • Neutralize Free Radicals: Alpha lipoic acid has been shown to Neutralize Free Radicals, as it’s a powerful antioxidant
  • Reduces Oxidative Stress: As an antioxidant, Alpha Lipoic Acid is known for its ability to reduce cellular damage and oxidative stress in the body, which helps to protect against age-related damages
  • Functions in Water and Fat: Unlike most antioxidants, like vitamins C and E, Natrol Alpha Lipoic Acid functions in both water and fat, making it a more robust and effective antioxidant
  • Supports Blood Sugar Health: Alpha Lipoic Acid is important for blood sugar health, encouraging glucose uptake by the body’s cells
Special Ingredients5-Hydroxytryptophan
BrandNatrol
Specific Uses For ProductAnti Aging and antioxidant support
Product BenefitsAnti-Aging
Item FormTablet
Diet TypePlant Based
Dosage FormTablet
FlavorUnflavoured
Allergen InformationMilk Free, Fish Free, Wheat Free, Peanut Free, Tree Nut Free, Egg Free
Material FeatureVegetarian

Alpha Lipoic Acid TR 600mg 45 TabletNatrol Alpha Lipoic Acid (ALA) is a powerful antioxidant that helps protect your cells from oxidative damage related to aging and environmental stress. ALA supplementation can support your energy metabolism and help rejuvenate your cells. ALA can also encourage glucose uptake by the body’s cells. Natrol Alpha Lipoic Acid TR 600 mg is 100% vegetarian and formulated with a controlled delivery system which releases ALA over the course of 12 hours to provide all day antioxidant and energy support.
Suggested Use As a dietary supplement Takes 1 tablet, one time daily, with a meal. – Or as directed by your healthcare professional.

QUALITY

Natrol delivers safe, effective, and trustworthy products that meet rigorous quality checks.

INNOVATION

We constantly push the frontiers of research to develop vitamins, minerals and supplements that deliver better outcomes for our consumers and improve the quality of their lives.

PEOPLE

People make things happen at Natrol. Here at Natrol, we foster an environment based on integrity, respect, and responsibility.

LIVE HEALTHIER LIVES

Natrol is committed to delivering the highest-quality products while remaining affordable for all.

5. Pure Encapsulations Alpha Lipoic Acid 200 mg

Pure Encapsulations Alpha Lipoic Acid 200 mg | ALA Supplement for Liver Support, Antioxidants, Nerve and Cardiovascular Health, Free Radicals, and Glucose Support* | 60 Capsules
  • Cellular Energy Support: A key component of the metabolic process, alpha lipoic acid produces energy in muscles and directs calories into energy production.*
  • Nervous System Support: Alpha lipoic acid modulates nitric oxide metabolite activity and promotes healthy microcirculation.*
  • Supports Glucose Metabolism: Alpha lipoic acid supports healthy glucose uptake and helps to maintain healthy glucose utilization.*
  • Pure Quality: Our supplements are made with only premium ingredients sourced from trusted suppliers and guided by our nutritional experts, then carefully manufactured and tested to verify their potency and purity.
  • Pure Difference: What makes us different isn't just our process or what goes into our supplements -- what we leave out matters, too. Pure Encapsulations products are FREE FROM wheat, eggs, tree nuts & peanuts, gluten, artificial colors, flavors & sweeteners, coatings and shellacs, GMOs, and unnecessary binders, fillers & preservatives.
BrandPure Encapsulations
Product BenefitsMetabolism Management
Item FormCapsule
Dosage FormCapsule
FlavorUnflavored
Item Weight0.1 Pounds
Unit Count60.00 Count
Item Dimensions LxWxH3.5 x 2 x 2 inches

Pure Encapsulations Alpha Lipoic Acid provides powerful antioxidant support to promote overall well-being.* Alpha lipoic acid is a naturally occurring compound in the body, where it plays a vital role in energy production, glucose metabolism, and nerve function. Our premium-quality supplement delivers 300 mg of alpha lipoic acid per capsule, providing 50 mg per serving.

The Truest Quality

What makes us different is the promise of goodness that goes into every one of our supplements. We take high standards seriously, which is why we’re the #1 most recommended professional supplement brand, ranked highest in quality and trust.^ ^Among brands surveyed, Nutrition Business Journal 2016, 2020, Kaiser Associates 2014.

Good from Start to Finish

When developing our products, we work in close collaboration with leading medical professionals and nutritional experts to create premium dietary supplements that you can feel good about. Our high-quality ingredients are backed by science with many of our formulations being included in more than 50 product-specific clinical studies in leading peer-reviewed journals.

FDA Disclaimer: These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Goodness at our Core

Pure Encapsulations was built with the purest of hearts and a plan to improve the wellness and wellbeing of others. This heartfelt commitment now extends to the planet as we move forward in sustainability initiatives and continue to support incredible organizations dedicated to leading the charge for a greener future.

6. Best Naturals Alpha Liopic Acid

Best Naturals Alpha Liopic Acid 600 mg 120 Count - ALA Alpha Lipoic Acid Powerful Antioxidant
  • Ala - Alpha Lipoic Acid is universal antioxidant which helps maintaining healthy blood glucose level*
  • Ala - Alpha Lipoic Acid supports vision and nerve function, directly recycle Vitamin C and indirectly recycle Vitamin E & Supports synthesis of glutathione.
  • No artificial color, flavor or Sweetener, No Preservatives, No Sugar, No Starch, No Corn, No Soy, No Egg, No Milk, No Lactose, No Gluten, No Wheat, No Yeast, No Fish. Sodium Free.
  • 600 mg of ALA - Alpha Liopic acid per capsule - 120 Capsules per bottle
  • Top QUALITY GMP CERTIFIED PRODUCTS - All Best Naturals products are manufactured in accordance with Good Manufacturing Practices (GMP), among the highest standards in the world -- Proudly Made in USA -- Purity & Potency Guaranteed
BrandBest Naturals
Product BenefitsEnergy Management
Item FormCapsule
Dosage FormCapsule
FlavorUnflavored
Age Range (Description)Adult
Allergen InformationSoy Free, Egg Free, Gluten Free, Milk Free, Lactose Free, Wheat Free, Fish Free
Material FeatureHypoallergenic
Item Weight0.25 Pounds
Unit Count120 Count

Alpha lipoic acid (aka ALA, lipoate or thioctic acid) is utilized as an antioxidant and co-factor in glycolysis. Glycolysis is the initial process in most of the body’s pathways to breakdown glucose into useful forms of energy. Though critical to life, ALA is not a vitamin because it can be synthesized from essential fatty acids and the amino acid L-cysteine. However, no food is rich enough to serve as a good source.

At Best Naturals, we have a quest that every human being on this planet will leave a healthy and happy life. That is why for us at Best Naturals has embarked on the unique journey of creating and selling highest quality supplements to help lead happy and healthy life. Best Naturals has a super growth trajectory, but we are determined to stick with some of the core values which define our integrity and passion towards our mission and vision. Here they go:

  • There is no compromise when health is at stake
  • Provide the highest-quality nutritional supplements according to the industry standards
  • Deliver the best product on time to keep the customer happy
  • Create a unique culture and work environment where ethics, honesty and employee excellence is recognized and believed

7. Source Naturals Alpha Lipoic Acid

Source Naturals Alpha Lipoic Acid 200 mg Supports Healthy Sugar Metabolism, Liver Function & Energy Generation - 60 Tablets
  • ULTIMATE PROTECTION. It is a critical component of an enzyme that generates acetyl coenzyme A, the start of the Krebs cycle that produces ATP in the mitochondria. ATP is the main source of energy for all muscle contractions and almost all other activities that our cells perform. Most of all, ALA is recognized as a powerful antioxidant because it has the unique ability to reactivate helpful compounds like vitamin C, glutathione, vitamin E, and CoQ10, enabling them to do more for your health.
  • SUPPORT YOUR BODY WITH ANTIOXIDANTS. It is a potent antioxidant and is active in both fat- and water-soluble regions of the cells. This makes ALA quite rare and this is why it is called “the universal antioxidant.” ALA also supports healthy sugar metabolism, liver function and energy generation.
  • A HIGHLY EFFECTIVE ANTIOXIDANT. ALA scavenges and terminates free radicals. The quenching of free radicals is a highly important aspect of healthy aging and immune health. ALA is a potent reducing agent and can reactivate other helpful antioxidants like vitamin C, vitamin E, and CoQ-10.
  • TRUSTED FOR OVER 35 YEARS. Source Naturals was created in 1982 by CEO Ira Goldberg to support each individual's potential to enjoy optimal health.
  • MANUFACTURED IN THE USA. Our facility is located in Scotts Valley California.
BrandSource Naturals
Product BenefitsEnergy Management
Item FormTablet
Dosage Form200
Item Weight0.01 Pounds
Unit Count60.00 Count
Item Dimensions LxWxH1.83 x 1.83 x 3.32 inches

Source Naturals Alpha Lipoic Acid Timed Release is designed to be released gradually throughout the day. It is a potent antioxidant and is active in both fat- and water-soluble regions of the cells. This makes ALA quite rare and this is why it is called “the universal antioxidant.

ALA also supports healthy sugar metabolism, liver function, and energy generation. It is a critical component of an enzyme that generates acetyl coenzyme A, the start of the Krebs cycle that produces ATP in the mitochondria.

ATP is the main source of energy for all muscle contractions and almost all other activities that our cells perform. Most of all, ALA is recognized as a powerful antioxidant because it has the unique ability to reactivate helpful compounds like vitamin C, glutathione, vitamin E, and CoQ10, enabling them to do more for your health.

The suggested use is 1 tablet daily with or without a meal. For maximum results include vitamin B complex, magnesium, and coenzyme Q10 with alpha-lipoic acid in your nutrition program. Please contact our in-house customer support if you have any questions.

Small changes in the product size & weight lead to lower carbon emissions.

We created Compact by Design to identify products that, while they may not always look very different, have a more efficient design. With the removal of excess air and water, products require less packaging and become more efficient to ship. At scale, these small differences in product size and weight lead to significant carbon emission reductions.

How to Choose the Best Alpha Lipoic Acid Supplement for You

We put together this complete buyer’s guide after presenting the top eight ALA formulas on the market to educate you on everything you need to know about alpha lipoic acid and its various health advantages. This is to verify that you choose the proper product before purchasing one.

However, before starting any ALA supplement, you should speak with your doctor.

What Is Alpha-Lipoic Acid and How Does It Work?

Alpha-lipoic acid is an organic fat-soluble and water-soluble substance found in all human cells. Acetate-replacing factor, Biletan, ALA, Thioctan, and Lipoicin are some of its other names. This naturally occurring fatty acid can also be found in foods such as yeast, spinach, broccoli, potatoes, and organ meats such as liver and kidney.

ALA is created by cell mitochondria, which helps enzymes convert foods like glucose into energy. The chemical contains antioxidant characteristics that aid in the battle against “free radicals,” which are waste products generated when the body turns food into energy.

The ALA in Its Many Forms

Supplements often contain synthetic copies of the naturally occurring type of alpha-lipoic acid (the R-isomer) or a combination of the R- and S-isomer forms.

Despite the fact that the R-isomer is the more active of the two isomers, most clinical research on ALA efficacy and side effects use mixed formulations. In addition, these blended formulations are frequently less expensive than R-isomer-only drugs.

When compared to its S enantiomer, research shows that the R enantiomer of ALA has better pharmacokinetic characteristics and bioavailability.

What Is the Function of Alpha Lipoic Acid?

The use of alpha-lipoic acid is linked to a number of various health benefits. The following are some of the most significant alpha-lipoic acid advantages:

Nerve Function Enhancement

Alpha-lipoic acid has been shown in recent research to support healthy neuronal function induced by hyperglycemia. Furthermore, because alpha-lipoic acid is quickly absorbed by the brain, it may aid in the protection of brain and nerve tissue.

It’s also being looked into as a treatment for strokes and other brain illnesses caused by free radical damage, such as dementia. There isn’t enough evidence to say if it works or not.

It has been proven to slow the progression of carpal tunnel syndrome in its early stages. Consuming alpha-lipoic acid before and after surgery for carpal tunnel syndrome has been shown to improve healing outcomes.

Diabetes Management

According to reliable research, alpha-lipoic acid helps to lower blood sugar levels. It can also help diabetic peripheral neuropathy patients who suffer from pain, burning, itching, tingling, and numbness in their arms and legs owing to nerve damage.

According to a study, taking alpha-lipoic acid supplements can assist people with type 2 diabetes to improve their insulin sensitivity and blood sugar control, as well as reducing the symptoms of peripheral neuropathy.

If you have neuropathy, your doctor should prescribe an alpha-lipoic acid dosage, so talk to him or her first.

Skin Aging is Decreased

When it comes to using alpha-lipoic acid creams for skin, research shows that they can help reduce the signs of skin aging. Researchers discovered that using an alpha-lipoic acid cream on the face reduced fine lines, skin roughness, and wrinkles while having no negative side effects in a human study.

When alpha-lipoic acid is applied to the skin, it permeates into the inner layers and protects the skin from the sun’s damaging UV rays.

Furthermore, applying alpha-lipoic acid before night boosts the levels of other antioxidants like glutathione, which protect the skin from injury and may help to slow down the aging process.

The Ordinary Alpha Lipoic Acid 5% is a potent therapy that improves skin tone and texture while also reducing scarring, pigmentation, lines, and wrinkles.

Side Effects of Alpha Lipoic Acid

Alpha-lipoic acid is considered to be reasonably safe, with few to no negative effects. In some cases, however, users may have minor symptoms such as nausea, rashes, or itching.

Adults can consume up to 2,400 mg without having any negative side effects, according to one study. Higher dosages are not recommended because there is no evidence that they provide further benefits.

Furthermore, animal studies have revealed that large dosages of alpha-lipoic acid have the following consequences:

  • Oxidation is accelerated.
  • liver enzymes are altered
  • Neuropathy caused by alpha lipoic acid
  • Harmful to the liver and breast tissue

Researchers are also looking into the effects of alpha-lipoic acid on thyroid tissue.

Conclusion

It is possible to purchase the best alpha lipoic acid products on the market. The modern industry has come up with many natural ingredients that are effective in treating several health conditions. These products are not only beneficial for keeping a check on health but also for some of the physical issues related to hair and skin. In order to make the best selection from the list of products available, people should consider getting suggestions from medical practitioners and friends who are already using these products.

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