7 Best Alpha Lipoic Acid For Neuropathy In 2022

Alpha-lipoic acid (ALA) is a molecule produced by the body and found in several foods, including organ meats, yeast, spinach, broccoli, and potatoes.

It’s a popular supplement due to its antioxidant properties, which can reduce oxidative stress and inflammation. It’s also known for taking the edge off symptoms of diabetes, accelerating weight loss, and improving skin health.

Although, there are so many to choose from and it can be hard to pick the one you actually need. So, after testing several models, as well as getting input from medical professionals and patients, We’ve decided to list what we think are the Best Alpha Lipoic Acids on the market today.

Editor’s Choice: Best Alpha Lipoic Acid For Neuropathy

Benefits Of Best Alpha Lipoic Acid

Fatty acids come in a kind known as alpha-lipoic acid, which is known for its anti-inflammatory and anti-oxidation properties in the human body. Alpha-lipoic acid Alpha-lipoic acid is produced naturally within the body, but it can also be obtained through the consumption of organic meat, vegetables, broccoli, and fruits. When it comes to reducing inflammation and protecting cells from oxidative damage, alpha-lipoic acid, which is sold as a dietary supplement, has demonstrated significant benefits. There are further advantages to taking the supplement, such as its ability to protect the body from hepatic disorders, ischemic heart disease, neurological degeneration that is typically associated with aging, diabetes, and other conditions. It does this by reducing inflammation and improving the function of nerve regeneration, which both help avoid diabetic foot ulcers.

7 Best Alpha Lipoic Acid Reviews

1. Superior Labs Alpha Lipoic Acid

Superior Labs Alpha Lipoic Acid - Pure NonGMO ALA 600mg 120 Vegetable Caps - Zero Synthetic Additives, Stearates, Fillers - to Support Healthy Blood Sugar, Nerve Health, Tingling Feet, Hands, Limbs

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Superior Labs’ Alpha Lipoic Acid (ALA) is an exceptional option for anyone with issues related to blood sugar, nerve health and tingling limbs. The beneficial ingredients come from cabbages and are free of synthetic additives like fillers and stearates. At Superior Labs, they have been working with ALA for more than a decade and have gone to great lengths to ensure that the supplements they offer provide the highest quality of ingredients.


Few are able to meet the rigorous requirements of the NSF, and even fewer already do. The quality of the facilities in which their products are manufactured has been verified by a third party and approved by NSF, which is widely regarded as being among the most rigorous quality manufacturing assurance companies in the business.

Absolute Purity

They believe in their products and they put all ingredients through rigorous testing to make sure they are 100% free of contaminants. You will never see unnecessary additives such as stearates, dioxides, glycerides or fillers other brands use to make manufacturing cheaper, faster and easier. In addition, they put all ingredients and products through rigorous testing to make sure they are 100% free of contaminants.

Powerful Anti-Aging Antioxidant

ALA is a unique and integral part of the body’s natural antioxidant systems. Their bodies need it to produce energy but only excess ALA – which can only be achieved through supplementation – will operate as a free-radical fighting antioxidant. Unfortunately, the body does not produce enough to keep up with the demands of daily living, let alone for their skin to look young and healthy.

Healthy Nerve Function, Blood Sugar and Tingling Hand

Healthy Nerve Function, Blood Sugar and Tingling Hand, Feet & Limbs contains powerful 600mg of pure ALA in a vegetable capsule for superior absorption. This product promotes healthy blood sugar levels, nerves and nervous system. Two capsules daily for at least six weeks is recommended for safe use.

2. Nutricost Alpha Lipoic Acid 600mg Per Serving

Nutricost Alpha Lipoic Acid 600mg Per Serving, 240 Capsules - Gluten Free, Vegetarian Capsules, Soy Free & Non-GMO

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ALA (Alpha Lipoic Acid) supplements are becoming more popular among consumers these days, because they provide metabolic energy support in the form of an antioxidant that works naturally with your body to maintain cellular health. Nutricost’s Alpha Lipoic Acid is a balanced source of this form of independent free-radical scavenging antioxidant. The dosage level is 600 mg per serving and each serving is provided in a vegetable capsule. ALA has been shown to be exceptionally effective at crossing the blood-brain barrier and transporting oxygen to the brain tissue, which helps reduce symptoms of central nervous system disorders related to oxidative stress.

High Quality

Alpha Lipoic Acid 600mg is a dietary supplement. It is Purified, Chelated and Therapeutic Grade Pure Alpha Lipoic Acid (ALA). This product contains a high quality source of ALA, with a high absorption rate.


Their Non-GMO Alpha Lipoic Acid is Gluten Free, Soy Free, Vegetarian Friendly and 3rd Party Tested. Made from Fennel and Garlic Extract, their ALA is manufactured in a GMP certified facility to ensure that each batch is consistent and of the highest quality.

GMP Compliant And FDA Registered

Everything they make is made in a GMP Compliant and FDA Registered Facility. They use the highest quality ingredients to ensure you are receiving the best products. Their facility is equipped with PETG bottles and caps, which are completely BPA free.

Each bottle

Each bottle contains 240 capsules of Alpha Lipoic Acid (120 -240 servings per bottle), making it one of the most convenient ways to take the benefits of this amazing antioxidant. The capsules themselves are made using vegetarian-sourced gelatin and are gluten-free, 100% vegan, and suitable for individuals following a Paleo diet or anyone who avoids ingredients derived from animals or gluten.  

3. Nature’s Bounty Alpha Lipoic Acid 200 mg 30 Capsules

Nature's Bounty Alpha Lipoic Acid 200 mg 30 Capsules

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Nature’s Bounty Alpha Lipoic Acid is a dietary supplement which helps the body to maintain a strong and healthy metabolism. Alpha lipoic acid mainly works on the central nervous system and also affects the heart, liver and kidneys. Since it improves the effectiveness of insulin, it also prevents the storage of extra fat. This weight management supplement comes with 200 mg of alpha lipoic acid in each capsule. It is also composed of other essential vitamins and minerals such as folic acid, zinc and molybdenum. This product is vegetarian, gluten free and sugar free.

Beneficial antioxidant support

Their best-selling antioxidant supplement is made with a multivitamin blend of antioxidants including Vitamin C and Vitamin E, as well as CoQ10, resveratrol, apple polyphenols and astaxanthin.

Free Radicals

Antioxidants are a source of natural antioxidants that help your body to fight free radicals. Free radicals can cause oxidative stress, which may result in cells being damaged. Antioxidants are natural substances found in fruits and vegetables, that work as antioxidants and can help slow or prevent the damage.(1)


Nature’s Bounty Alpha Lipoic Acid is a powerful antioxidant that supports the immune system, as well as circulation, helping to neutralize free radicals and help oxygenate the heart, brain and muscles. This formula is derived from non-GMO sunflower seeds.

Food and Drug Administration

These statements have not been evaluated by the Food and Drug Administration (FDA). These products are not intended to diagnose, treat, cure or prevent any disease. Please consult your doctor before starting any exercise or nutritional supplement program or before using these or any product during pregnancy or if you have a serious medical condition.

4. Doctor’s Best Alpha-Lipoic Acid, Non-GMO

Doctor's Best Alpha-Lipoic Acid, Non-GMO, Gluten Free, Vegan, Soy Free, Helps Maintain Blood Sugar Levels, 600 mg 180 Veggie Caps

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Doctors Best Alpha Lipoic Acid is a non-methylated, water-soluble antioxidant that supports healthy blood sugar levels and maintains the metabolic functions. Supplementation of Alpha-Lipoic Acid can help maintain the cellular levels of glutathione, which is one of the most powerful antioxidant compounds in the body.

Support With Antioxidant

Alpha Lipoic Acid (ALA) is an antioxidant that supports the regeneration of other antioxidants. It is readily available to the body to help scavenge free radicals and protect against oxidative stress. ALA also appears to function as a coenzyme in both antioxidant and metabolic functions. ALA’s unique functionality makes it an effective supplement for maintaining healthy cells, supporting overall health, and fighting the effects of aging.

Body’s Defenses Against Free Radicals

Vitamin C supports the body’s natural defenses against free radicals. Vitamins C and E play important roles in the body’s antioxidant defense system. Vitamin C has a complementary action to Vitamin E, and facilitates its efficient functioning in tissues and cells. This potent antioxidant can recycle antioxidants such as Vitamin E that have the ability to quench a wide variety of free radicals. Also supports the functioning of other antioxidants that are present in tissues and cells.

Supporting Overall Well-Being

ALA has shown to be incredibly beneficial in supporting overall well-being. Studies have shown ALA can help maintain healthy glucose metabolism, supports healthy aging and cognitive function and brain health, eye health and cardiovascular health.

5. NOW Supplements, Alpha Lipoic Acid 600 mg with Grape Seed Extract & Bioperine®, 120 Veg Capsules

NOW Supplements, Alpha Lipoic Acid 600 mg with Grape Seed Extract & Bioperine®, Extra Strength, 120 Veg Capsules

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Alpha lipoic acid (ALA) is naturally produced in the human body in very small amounts, but is also available in some foods. ALA is unique in that it can function in both water and fat environments. ALA promotes the production of glutathione and can also recycle vitamins C and E, thereby enhancing their antioxidant activities. In addition, ALA may help to maintain healthy neural tissues, promote proper glucose metabolism and support healthy cardiovascular function. From NOW Foods Upgraded with Bioperine® to enhance bio-availability – an exclusive process to imbue nutrients with superior systemic absorption.


CRC Kosher, Dairy Free, Egg Free, Made without Gluten, Nut Free and Soy Free. Ingredients: 100% Pure Aloe Vera Juice, Soluable Collagen Peptides and Vitamin C.

GMP Quality

NOW’s commitment to quality assurance is reflected in the fact that they are one of the few brands to have an independent, third-party GMP certification. NPA A-rated GMP certification means that every aspect of the NOW manufacturing process has been examined, including their laboratory/testing methods (for stability, potency, and product formulation).

Free Radical Scavenger

Take 1 NOW® Alpha Lipoic Acid 600 mg veggie capsule daily, preferably with a meal. This extra strength product has more alpha lipoic acid (600 mg per capsule) than their regular strength product (100 mg per capsule). Alpha Lipoic Acid helps the body metabolize fat and carbohydrates and generate cellular energy. It is also a potent antioxidant that helps prevent damage to your cells caused by free radicals.

Grape Seed Extract with Bioperine®

Alga Laffa-Grape Seed Extract with Bioperine® is a scientifically formulated dietary supplement that combines the antioxidant support of Grape Seed Extract with the phenolic compounds and amino acid precursors of AlfaLfa. These ingredients help maintain healthy cardiovascular and neural tissues, promote proper glucose metabolism and support the body’s antioxidant defenses for peak physical performance.

6. Pure Encapsulations Alpha Lipoic Acid 600 mg

Pure Encapsulations Alpha Lipoic Acid 600 mg | ALA Supplement for Liver Support, Antioxidants, Nerve and Cardiovascular Health, Free Radicals, and Glucose Support* | 120 Capsules

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Pure Encapsulations Alpha Lipoic Acid 600mg is another great natural supplement that supports your body’s ability to rid itself of toxins and protect your metabolism from free radicals. This means that Pure Encapsulations Alpha Lipoic Acid 600 mg can help support your liver and improve the health of your blood vessels, nerve cells, and heart.

Pure Quality

Their supplements are made with only premium ingredients sourced from trusted suppliers and guided by their nutritional experts. Their supplements are manufactured under a quality program that entails careful testing and verification of potency and purity.

Cellular Energy Support

Cell Energy Support is a key component of the metabolic process, producing energy in muscles and directing calories into energy production.* Cell Energy Support is made up of natural ingredients that are packed full of antioxidants to help support healthy energy production.

Glucose Metabolism

Alpha lipoic acid is a coenzyme in the metabolic pathway for carbohydrate, fat and protein metabolism. Alpha lipoic acid plays a critical role in the production of enzymes that maintain cell structure, nerve transmission and energy balance. Alpha lipoic acid supports healthy glucose uptake and helps to maintain healthy glucose utilization.

Pure Difference

Pure Encapsulation supplements are formulated with only the finest ingredients, those that are fully metabolizable and easily assimilated by the body. They contain no wheat, eggs, tree nuts or peanuts (contains GLUTEN) and they’re free from artificial colors, flavors and sweeteners, coatings and shellacs as well as GMOs. These dietary supplements are also free from unnecessary binders, fillers & preservatives.

7. Solgar Alpha Lipoic Acid 200 mg Vegetable Capsules

Solgar Alpha Lipoic Acid 200 mg, 50 Vegetable Capsules - Antioxidant Support - Helps to Recycle Glutathione, Vitamin C & E, CoQ-10 - Non-GMO, Vegan, Gluten Free, Dairy Free, Kosher - 50 Servings

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Solgar Alpha Lipoic Acid 200 mg Vegetable Capsules are the perfect addition to your daily regimen, whether you’re looking to give your skin a boost, reach energy levels unseen since your 20s, or keep your mouth healthy and happy. Inside each of these capsules, you’ll find 100% natural Alpha Lipoic Acid. This key nutrient has been proven to help fight free radicals in the body. Each capsule includes 200 mg of Alpha Lipoic Acid along with vegetable cellulose for superior bioavailability.

Easy To Take

Easy to take Solgar Alpha Lipoic Acid 200 mg. No better way to maintain your antioxidant levels and fight off free radicals than by taking Easy to take Solgar Alpha Lipoic Acid 200 mg in a capsule, delivered directly into your bloodstream. The easy absorption of EASY TO TAKE Solgar Alpha Lipoic Acid 200 mg gives you a daily dose that’s absorbed directly into your system for maximum results.

Rich In Antioxidant

Rich in antioxidant Solgar Alpha Lipoic Acid 200 mg is a fatty acid found naturally in the body It is soluble in both water and lipid based tissues and is sometimes used with vitamins C and E. Alpha Lipoic Acid helps the body produce energy by aiding in glucose metabolism. Alpha Lipoic Acid can help reduce the appearance of wrinkles while supporting healthy blood vessels and nerve function.

Natural Wellness

They believe that cleaner is better, they craft their vitamins and minerals in small batches to help ensure consistency and purity from bottle to bottle. The result is a product free from unnecessary additives and preservatives, one that you can truly feel good about taking every day.

Gold Standard

SOLGAR Gold Standard guarantees that their products meet their industry recognized “Gold Standard” for excellence, made using naturally sourced ingredients and innovating since 1947. With strict specifications on every level of quality, from sourcing raw materials to testing finished formulas, these manufacturing processes set guidelines for their ongoing product development.

What To Consider When Buying Best Alpha Lipoic Acid For Neuropathy

Best Alpha Lipoic Acid For Neuropathy

Finding the best alpha lipoic acid for neuropathy can be a daunting task, especially if you’ve never used this type of supplement before. There are many different manufacturers and products on the market, and not all of them are created equal.

There are many different brands of alpha lipoic acid on the market today—and choosing the best one can be overwhelming at times. Here are some things to consider when looking for the best alpha lipoic acid for neuropathy:


The quality of your supplement is important because it can affect how well it works, or whether it works at all. You should always buy from reputable brands that have been tested by third-party laboratories so that you know exactly what’s in their product and how much is present in each dose.


Another important factor when choosing an alpha lipoic acid supplement is purity. This means that there shouldn’t be any additives, fillers or other ingredients besides those listed on the label (such as magnesium stearate). If possible, choose one that’s been certified organic as well.


Different brands offer different dosages of alpha lipoic acid, so look into how much they offer before buying a product. You may need more than one capsule per day depending on your dosage needs and your health conditions, so choose a brand.


Choose a brand that meets your needs. Some supplements contain only one form of alpha lipoic acid; others have combinations of multiple forms of the compound.

Forms of Alpha Lipoic Acid

Alpha lipoic acid comes in two forms: R-alpha lipoic acid and S-alpha lipoic acid. The difference between these two forms is that R-alpha lipoic acid has an additional molecule attached to it which makes it more water soluble than S-alpha lipoic acid. This means that R-alpha lipoic acid does not need bile salts for absorption into the bloodstream and can be absorbed directly from the intestines into the bloodstream where it goes on to do its job.

Best Alpha Lipoic Acid For Neuropathy-FAQs

What is alpha-lipoic acid used for?

In addition to its use as an antioxidant supplement for general health, alpha-lipoic acid is also utilized for the treatment of diabetes and the alleviation of symptoms associated with nerve damage. It is also possible to utilize it in order to assist reduce the adverse effects of aging on the health of the skin.

Is alpha-lipoic acid safe to use on a daily basis?

Yes, alpha-lipoic acid can be taken everyday. Daily supplementation has been shown to have no significant negative effects in controlled studies over the course of a year and to be well-tolerated in studies lasting up to four years.

Why is R-Lipoic Acid superior to (R/S) alpha-lipoic acid?

R-Lipoic Acid is the natural form of lipoic acid, and it is the specific type of lipoic acid that the body produces naturally and needs. Because the body “recognizes” R Lipoic and “knows” how to use it, it possesses a potency that is substantially greater than that of Alpha Lipoic.

According to research, not only does the human body have trouble absorbing the unnatural (S) version, but it may also prevent the natural R-Lipoic Acid from exhibiting its most important capabilities!

Who should not take alpha-lipoic acid?

Alpha-lipoic acid does not pose any health risks to the majority of people. Alpha-lipoic acid, on the other hand, has the potential to bring your blood sugar level to an unsafely low level if you are already taking medicine to control diabetes or lower your blood sugar.

When is the best time to take lipoic acid?

It is recommended that diabetics take R-lipoic acid on an empty stomach, between half an hour and two hours before a meal, or three hours after eating, and that they do it in the morning or early afternoon, if possible.

If you do not have diabetes, you are free to take it whenever you like, either with meals or on an empty stomach. Consuming food will cause the drug to be absorbed more slowly, but it will have no impact on its effectiveness.


Alpha-lipoic acid is contained in every human cell. It converts glucose into energy using oxygen. Diabetes, nerve discomfort, weight reduction, heart disease, and mitochondrial illnesses are helped by it. Overindulging seems to induce ALA’s minor side effects. ALA interacts with medicines like other supplements. Before deciding if you may safely utilize ALA, a doctor must fully assess your health.

If the supplement department at your favorite grocery shop feels packed, you have more product choices. Unfortunately, you have more options. More options can confuse.

You shouldn’t expect immediate benefits from supplements. Any supplement impact will likely be mild and take time to appear. Supplements support health, but they don’t treat or cure sickness or perform miracles. If a supplement claims to save lives, it’s probably a scam.

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